About Us


The Yash Gandhi Foundation is a registered 501(c)(3) not for profit organization. There are no over-head costs or salaries paid out by this foundation. All contributions are 100% directed to fund for research in I-cell. The foundation was created in 2002 after the parents of Yash Gandhi found out that he had a rare terminal genetic disease that had no cure. As any parent would do, we are taking the challenge to help find a cure for this terrible disease so that it can help other children in the future.


The foundation's goal is to provide grants or fund academic institutions or individual researchers who are currently conducting research in the field of lysosomal storage disorders (overall term for storage disorders that includes I-cell). The grant monies are to be used solely for the purposes of furthering the research in I-cell disease and not for compensation, salaries or equipment. The institution or individual researchers will be required to provide a grant proposal which outlines the purpose of the research study, obligates the grantee to use the funds for research purposes only, provides a report on how grant funds are used and a final study report on the results of the study.


I-cell disease is an inherited lysosomal storage disorder. People with I-cell disease have lysosomal enzymes in their bloodstream that lack an uncommon sugar, called mannose-6-phosphate (M6P), that is always found on enzymes in the lysosomes of normal cells. One unique feature of this disease is the presence of phase-dense cytoplasmic "inclusions" in the fibroblasts of patients. These cells are termed inclusion cells, or I-cells; thus, the disease is designated I-cell disease.

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